Lindacals


OTC

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Lindacals – regulator of calcium and phosphorus metabolism.

Composition

Each soft gelatin capsule contains:

Alfacalcidol BP 0.25 mcg;

Calcium Carbonate BP equivalent to Elemental Calcium 200 mg;

Excipients q.s.

Approved Colours used in capsule shell

Indications for use

Lindacals should be used with the following indications:

  • Osteoporosis;
  • Renal bone disease (Renal osteodystrophy);
  • Hypoparathyroidism;
  • Hyperparathyroidism (with bone disease);
  • Rickets;
  • Osteomalacia;
  • Chronic renal failure;
  • Conditions associated with gastric hyperacidity.

Mode of application

The dosage and administration of Lindacals should be adjusted according to the need of the patient.

The initial dosage is:

Adults: 1-2 capsules / day

Elderly patients: 1 capsule /day

The exact dosage in osteoporosis is not defined, however the various clinical studies have used the
dosage of alfacalcidol in range of 0.5 – 1 mcg/day with or without calcium in treatment of osteoporosis.

Not recommended in children.

Subsequent dose titration can be done according to the clinical and biochemical response so as to
avoid hypercalcaemia.

Most adults respond to doses of 1 to 3 mcg/day of alfacalcidol and 0.25 – 3 gm of calcium carbonate.

Indices of response, in addition to a rise in plasma calcium, may include a progressive reduction in alkaline phosphatase, a reduction in parathyroid hormone levels, an increase in urinary calcium excretion in patients with normal renal function, bone radiography and histological improvements.